Treatment of lymphoma

Written by Dr.Md.Redwanul Huq (Masum)
Monday, 20 June 2011 15:33

Treatment of Hodgkin’s lymphoma:

General treatment:

1. Adequate hydration
2. Use of antibiotics for infection control
3. Management of anemia, blood transfusion if needed

Specific treatment:

1. Stage IA, IIA (with involvement of 3 or less areas) – radiotherapy is the choice, if relapse- chemotherapy should be given.
2. Stage IIIA (with involvement of spleen), IV, all stages with B symptoms, stage II with involvement of 3 or more areas – chemotherapy is the choice.

Chemotherapy is given as one of the following:

* ABVD (Adriamycin, Bleomycin, Vincristine, Dacarbazine)
* MOPP (Mustine hydrochloride/ mechlor-ethamine, Vincristine, Procarbazine, Prednisolone)
* COPP (Cyclophosphamide, Vincristine, Procarbazine, Prednisolone)
* ChlVPP (Chlorambucil, Vincristine, Procarbazine, Prednisolone)

Treatment of Non-Hodgkin’s lymphoma:

General treatment:

1. Adequate hydration
2. Use of antibiotics for infection control
3. Management of anemia, blood transfusion if needed

Specific treatment:

a) Stage  – I(A)- radiotherapy or surgery
b) Stage- I(B),II ,III, IV – chemotherapy.
Chemotherapy is given as following:
a) In low grade NHL: Single drug regimen with Cyclophosphamide or Chlorambucil (oral)
b) In intermediate or high grade NHL:
CHOP (C – cyclophosphamide, H – adriamycin, O – vincristine, P – prednisolone).

To know the Generic and Trade names of the above mentioned drugs and their available formulations in Bangladesh click here.


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